Advanced Spectroscopy

The topics discussed include modern applications of fluorescence/phosphorescence and Raman spectroscopy. Attention will be given to energy transfer mechanisms and the use of fluorescent probes, high-resolution fluorescence at cryogenic temperatures, single-molecule spectroscopy and coupling to analytical separation techniques. Raman spectroscopic topics will include surface-enhanced Raman, resonance Raman, time-resolved Raman and non-linear Raman techniques. Instrumental aspects, such as laser excitation, time-resolved detection, polarization and imaging will also be covered in this course.

 

Recent examples of the use of these techniques in a chemistry, medical, environmental, industrial, forensic or space research context will be discussed on the basis of literature presentations by the students. The course also includes a set of fluorescence and Raman experiments at VU LaserLaB. In small groups the students will carry out a set of experiments, of which the results will be laid down in a report and an oral presentation.

 

The student teams will also prepare a presentation on a recent literature article, to be given and discussed in class.

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COURSE FACTS

Study Credits

6 ECTS

TYPE

Elective course

CATEGORY

Advanced

INSTITUTION

VU Amsterdam

CATALOGUE NO.

52548ADS6Y

TIME PERIOD(S)

Semester 2, Period 6

COORDINATOR

dr. Freek Ariese

LANGUAGE

English

STAFF

dr. Freek Ariese

PRE-KNOWLEDGE REQUIRED

Background knowledge of molecular spectroscopic techniques, in particular fluorescence and Raman, is expected (e.g. MSc Chemistry courses Spectroscopic Analysis or Microscopy and Spectroscopy).

CONTACT

Education Desk FNWI
Science Park 904
B1
020 5257100

servicedesk-esc-science@uva.nl

Intended Learning Outcomes

  • To acquire a deeper insight into the basic principles and modern developments of molecular spectroscopy in (bio)analytical chemistry, with emphasis on fluorescence/luminescence and Raman techniques.
  • To become familiar with recent literature on the use of these techniques in a variety of applications.
  • To improve written and oral presentation skills.
  • To acquire practical skills in modern (laser) spectroscopy.

Chemometrics & Statistics teaches you how to distill useful information generated by analytical methods.

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